Feng Laboratory McGovern Institute For Brain Research 43 Vassar Street, Office: 46-3133 Cambridge, Massachusetts 02139 Phone: (617) 715-4920 Website: fenglaboratory.org. Steven Hyman, M.D. Research (Aboobaker Lab.) His Ph.D. thesis was completed at Harvard Medical School in the lab of Michael Greenberg. However, research on the predictive potential and clinical importance of mitophagy-related genes (MRGs) in hepatocellular carcinoma (HCC) is currently lacking. From 2008 to 2019, Sheng was vice-president of neuroscience at Genentech, a leading biotech company, where he led research and drug discovery efforts for major diseases of the nervous system. - Investigating stem cells, regeneration and ageing using Planarian flatworms. By taking the advantage of next-generation sequencing technique, he uses bioinformatics approaches to investigate features of B cell repertoires, and to study mechanisms modulating the maturation process of broadly HIV-1 neutralizing antibody lineages in humans and animal models, with the aim of finding an optimal HIV . Chan School of Public Health to study the genetics of severe mental illness, has recruited more than 42,000 participants in Ethiopia, Kenya, Uganda, and South Africa. Work with wet-lab biologists to design and implement appropriate experiments for future computational analysis in areas such as neurophysiology and behavior. We are seeking a motivated Computational Associate II (CA) to join the Sheng Lab at the Broad Institute of MIT and Harvard. TJ is an Instuctor in Dr. Ben Neale and Morgan Sheng's groups. Dr. Sheng Ding is currently William K. Bowes, Jr. Background and aimsAs a result of increasing numbers of studies most recently, mitophagy plays a vital function in the genesis of cancer. The EWSC is catalyzing a new field of interdisciplinary research at the intersection of data science and life science, aimed at improving human health. Find out how to join the Broad as an employee or associate member. . The Stanley Center aims to reduce the burden of serious mental illness by contributing new insights into pathogenesis, identifying biomarkers, and paving the way toward new treatments. Morgan Sheng is a core institute member of the Broad Institute of MIT and Harvard, where he serves as co-director of the Broads Stanley Center for Psychiatric Research. A physician and a scientist, Morgan Sheng is author of more than 200 peer-reviewed publications focused on the molecular cellular biology of synapses and synaptic plasticity, and pathogenic mechanisms of neurodegenerative diseases. Sign in to create your job alert for Research Scientist jobs in United States. Sheng is an elected Fellow of the Royal Society (UK), the Academy of Medical Sciences (UK), and the AAAS. Institute Member, Broad Institute of MIT and Harvard Office: 46-3143A / Phone: (617) 715-4898 . Job functions Engineering, Information Technology, Operations. This center is developing new paradigms and technologies to scale the discovery of biological mechanisms of common, complex diseases, by facilitating close collaborations between the Broad Institute and the Danish research community. The scope will include integration with other internal and external genomics datasets. 2017 Sep 4;214(9):2611-2628. The Klarman Cell Observatory is systematically defining mammalian cellular circuits, how they work together to create tissues and organs, and are perturbed to cause disease. $160,000.00. Sheng spent the past 10 years at Genentech, a preeminent biotech company, as Vice-President of Neuroscience. The Eli and Edythe L. Broad Institute of MIT and Harvard (IPA: / b r o d /, pronunciation respelling: BROHD), often referred to as the Broad Institute, is a biomedical and genomic research center located in Cambridge, Massachusetts, United States.The institute is independently governed and supported as a 501(c)(3) nonprofit research organization under the name Broad Institute Inc., and it . The EWSC is catalyzing a new field of interdisciplinary research at the intersection of data science and life science, aimed at improving human health. In back-fill mining, how to rapidly increase the concentration of tailings is an important problem facing mining engineers. Professor, Department of Otolaryngology - Head and Neck Surgery; . Broad Institute 4.0. . Distinguished Investigator and Professor at Gladstone Institute of Cardiovascular Disease, and Department of Pharmaceutical Chemistry, University of California San Francisco. Feb 2023 - Present2 months. There he built and led a world-class neuroscience department and research program focused on elucidating pathologic mechanisms and developing new treatments for neurodegenerative diseases and pain, and illuminating pathways that are of basic scientific interest as well as therapeutic relevance. The Chen Lab. Pursuing these investigations will advance our knowledge of fundamental processes that may affect human neurological disorders. Zhe Ji, Ph.D. Assistant Professor Postdoc in Systems Biology, Harvard Medical School Postdoc in Computational Biology, Broad Institute of MIT and Harvard Ph.D. in RNA Genomics, Rutgers University E Core Institute Members have their primary laboratories in the Broad Institute facilities. At Genentechhe built and led a world-class neuroscience department and research program focused on elucidating pathologic mechanisms and developing new treatments for neurodegenerative diseases and pain, and illuminating pathways that are of basic scientific interest as well as therapeutic relevance. Many members of the faculty hold joint appointments with other departments at MIT and with outside institutions. Dejanovic B, Huntley MA, De Mazire A, Meilandt WJ, Wu T, Srinivasan K, Jiang Z, Gandham V, Friedman BA, Ngu H, Foreman O, Carano RAD, Chih B, Klumperman J, Bakalarski C, Hanson JE, Sheng M. Neuron. Neuron 29 (2), 353-366, 2001. The transesterification of ethyl butyrate with 1-butanol to give butyl butyrate catalyzed by Novozym 435 was performed in a batch slurry reactor and in a packed-bed microreactor. Just another site. 2018 Dec 19;100(6):1322-1336.e7. The observed reaction rate is . He obtained his B.S. Sheng's laboratory focuses on the mechanisms regulating axonal transport of mitochondria, endocytic organelles, and synaptic cargo and their impact on axonal homeostasis, synaptic function and neurodegeneration. University of Minnesota 4.2. his work to improve single-cell research protocols and technologies and how he transitioned from dentistry to life in a lab.Read more . This researcher will work in close collaboration with laboratory scientists on analysis of a range of projects with a strong emphasis on bulk RNA-seq and single cell approaches. NE30-6031. InBRAIN Collaboration Data Sharing Policy, Molecular and Cellular Neuroscience Program, Computationally-Enabled Integrative Neuroscience Program. Sheng started his academic career, centered on molecular and cellular neuroscience, in 1994 at Massachusetts General Hospital and Harvard Medical School, and later moved to MIT as the Menicon Professor of Neuroscience. A physician and a scientist, Morgan Shengis author of more than 200 peer-reviewed publications focused on the molecular cellular biology of synapses and synaptic plasticity, and pathogenic mechanisms of neurodegenerative diseases. Sheng received a B.A. far beyond the soil depth of 100-200 cm in other lab-column or on-site studies (Sheng et al., 2021). Massachusetts Institute of Technology 43 Vassar Street, Bldg. The Broad Institute of MIT & Harvard is looking for outstanding postdoctoral scholars to join the laboratory of Morgan Sheng, Co-Director of the Stanley Center for Psychiatric Research, The mission of the Stanley Center is to improve the lives of patients suffering from serious mental . Kingston, Ontario, Canada. Researchers anywhere can explore more than 6,000 drugs in the hub and search for possible new uses for them to jump-start new drug discovery. Learn about Broad Institute's mentored research offerings for high school students, college students, and recent college graduates. As Co-Director of the Stanley Center, Sheng will work with Stanley Center Director Steven Hyman to shape the centers scientific vision and direction, in addition to overseeing the centers therapeutic efforts, in conjunction with the Broads Center for the Development of Therapeutics. Nathaniel earned his MA in psychology from Boston University in 2022 William Ned Martenis is a therapeutics group research associate affiliated with the Pan and Sheng labs, where he primarily develops, troubleshoots, and runs high-throughput assays designed to better Kate graduated from American University in 2016 with a BA in Psychology. . . Sheng Gong currently works at the Department of Materials Science & Engineering, Massachusetts Institute of Technology. Associate Investigator, Broad Institute of Harvard/MIT Investigator, HHMI. The Broad Institute of MIT & Harvard is looking for outstanding postdoctoral scholars to join the laboratory of Morgan Sheng, Co-Director of theStanley Center for Psychiatric Research, The mission of the Stanley Center is to improve the lives of patients suffering from serious mental illnesses, through groundbreaking basic and translational research. Postdoctoral Associate - Sheng Lab Cambridge, MA $47K - $89K ( Glassdoor est.) - Identified telomerase isoforms by integrating NGS and RACE data: Designed and performed experiments (RACE) and sequence analyses (bash). . 910: 2001: PDZ domains: structural modules for protein complex assembly. Get alerts to jobs like this, to your inbox. I am excited to return to academia and establish a research lab at the Broad, said Sheng. From Lab to Real Life: How A*STAR supported a scientist's entrepreneurial journey. All Companies Boston University (6) Brigham & Women's Hospital(BWH) (3) Northeastern University (2) Veeva (2) University of Massachusetts Medical School (2) Veeva Systems (2) Dana-Farber Cancer Institute (2) Berklee College of Music, Incorporated (1) The Broad Institute, Inc. (1) Mitsubishi Electric Research Laboratories (1) Suffolk University (1) Broad Institute (1) Boston Conservatory at . Software Engineer. Following postdoctoral research in the lab of Lily Jan at the University of California, San Francisco, Sheng served as a faculty member in the Department of Neurobiology . Working with Addgene, Broad Institute has shared CRISPR genome-editing reagents with researchers at more than 3,200 institutions in 76 countries. We are a team of scientists studying the genetic basis and molecular mechanisms underlying schizophrenia and other brain disorders.

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